daily divided into two dosages Maximum 3–7 days without evidence of seizures Electroencephalography monitoring of patients with Hunt and Hess grade IV and V Extraventricular drainage Emergent ...

The CHAIN trial evaluating FYTF-919 for acute intracerebral haemorrhage by Jianwen Guo and colleagues1 marks an advancement in assessing traditional therapies while raising important methodological ...

The primary outcome measure was analyzed by logistic regression, with treatment, age, sex, baseline volume of intracerebral hemorrhage, prestroke modified Rankin scale score, and location ...

Tranexamic acid (TXA) has been shown to reduce bleeding in elective surgery and there is evidence that short courses of TXA can reduce rebleeding in spontaneous intracranial haemorrhage.

We appreciate the feedback on and constructive criticism of the CHAIN trial,1 where, as in all complex projects, there were various challenges, many of which were unforeseen. The result—an overall ...