Figure 1: Schematic of RAG-mediated DNA binding and cleavage. Here we report the crystal structure of the mouse RAG1 NBD in complex with a 14-mer DNA molecule containing the nonamer. The NBD ...

Researchers have developed a new fluorescent label that gives a clearer picture of how DNA architecture is disrupted in cancer cells. The findings could improve cancer diagnoses for patients.

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...

The crystal structure of human RXRα–LXRβ heterodimer bound to its cognate DNA element, with agonists and a coactivator peptide, is now solved. The heterodimer shows an X-shaped organization ...

(2009, October 11). 3-D Structure Of Human Genome: Fractal Globule Architecture Packs Two Meters Of DNA Into Each Cell. ScienceDaily . Retrieved May 9, 2025 from www.sciencedaily.com / releases ...

James Watson and Francis Crick revealed the structure of DNA — the genetic instructions in all living things — 70 years ago in the journal Nature. Watson and Crick could not have succeeded ...

In the DNA fiber assay used in this study, cells labeled with IdU (green) and CldU (red) nucleotide analogs were sorted into substages of S phase before being subjected to the DNA fiber assay.

Cell biologists and chemists reveal how viral DNA traffics in human cells. They have developed a new method to generate virus particles containing labeled viral DNA genomes. This allowed them to ...

In 1963, Popular Science reported on the Nobel Prize-winning discovery, and Rosalind Franklin⁠—the woman who was left out of the accolades.

A piece that aired on NPR this week about the discovery of DNA's structure neglected to mention the significant contribution of Rosalind Franklin to that scientific milestone.