When YouTube survival experts Kaduche and Wynn discover the world's destruction will be man-made, it's up to them to thwart the mysterious forces trying to end the world before it's too late.

Last Man on Earth Cast at Comic Con 2015 Comic Con 2015 Last Man on Earth panel preview: Everything you need to know 'The Last Man on Earth' finale: Will Forte on that double cliffhanger ending ...

An epidemic has killed off all of the fertile men on earth, except for Elmer Smith, a hillbilly who lives out in a cabin in the Ozarks, when he is discovered, every woman on the planet begins ...