In mice with Leigh Syndrome—the most common childhood mitochondrial disease—the HypoxyStat drug extended lifespan by more than three-fold and reversed brain damage and muscle weakness ...

A number of clinical syndromes are currently believed to be associated with mitochondrial disease. Possible examples include Pearson syndrome, Leigh syndrome, progressive external ophthalmoplegia ...

The research group also demonstrated in both mice and fibroblasts from children with the disease that CBD improves cellular function. Leigh syndrome is a rare mitochondrial disease particularly ...

Neither cranial MRIs nor post-mortem reports were available to confirm symmetric midbrain or brainstem necrosis to definitively confirm Leigh syndrome ... fulfill the 'disease causing' criteria ...

Mitochondrial diseases affect approximately 1 in 5,000 people worldwide, causing debilitating symptoms ranging from muscle weakness to stroke-like episodes.