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Study sheds light on the crucial role of glutamate tRNA fragments in brain aging and Alzheimer's diseaseMitochondrial Glu-5'tsRNA-CTC disrupts the binding of mt-tRNALeu and leucyl-tRNA synthetase 2 (LARS2), impairing mt-tRNALeu aminoacylation and mitochondrial-encoded protein translation. Defects in ...
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