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Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability. Researchers from the Bhogaraju Group at ...
Dublin, May 07, 2025 (GLOBE NEWSWIRE) -- The "Ligase Market - A Global and Regional Analysis: Focus on Product, Source, Application, End User, and Country - Analysis and Forecast, 2025-2035 ...
By searching through available genome sequence data, we have found many types of related ligase enzymes. We are confident that using these ligases we will be able to assemble longer peptides for a ...
Scientists have pinpointed how a special class of plant-derived enzymes, known as peptide ligases, work to join proteins together -- an important process in the development of drugs, for example ...
The E4 ligase UFD-2 is required for apoptosis induced by DNA damage in C. elegans, and for the resolution of RAD-51 foci during homologous recombination-dependent repair, thus coordinating these ...
University researchers developed a new ligase, an enzyme that joins together strands of DNA or RNA and has applications in biotechnology and diagnostics, as described in an Oct. 7 paper in RNA Biology ...
3-D structure of the evolved enzyme (an RNA ligase), using 10 overlaid snapshots. In the top region, the overlays show the range of bending and folding flexibility in the amino acid chain that ...
The researchers looked at a ubiquitin ligase enzyme named FBXL2, known to degrade proteins at various cellular membrane compartments. They found that by attaching or detaching a fat molecule or ...
The structure indicates that this artificially selected ribozyme uses reaction mechanisms that are much like those used by naturally occuring enzymes, Robertson said. “The L1 ligase appears to use ...