A research team has identified the transcription factor Lhx2 (LIM homeobox protein 2) as a key regulator in hepatic stellate ...

A guardian molecule ensures that liver cells do not lose their identity. The discovery is of great interest for cancer medicine because a change of identity of cells has come into focus as a ...

Researchers developed a new gene-editing strategy that dramatically boosts the effectiveness of gene therapies in the liver, a breakthrough that could lead to new treatments for about 700 genetic ...

This suggests these cells may be useful as new therapeutic targets for various liver conditions. The work appears in the journal Immunity. Macrophages are specialized immune cells located in every ...

However, observations carried out with a phase-contrast microscope on isolated living liver cells from animals kept in hypoxia indicate that vacuoles are not visible in non-fixed, unstained cells.

Gene editing is already being used to treat a handful of rare genetic diseases; however, most therapies involve breaking or ...

The 2019 Nobel Prize in Physiology or Medicine was awarded to three researchers who had discovered the hypoxia-inducible factor 1-alpha (HIF-1α), the key protein that determines how each cell ...

We can consider the tumour as a bandit’s base in a village, from which a community of different functional units grows — the millions of cells involved ... levels, or hypoxia, result from ...

HHMI researchers solve a longstanding mystery about the origin of new cells in the liver. Howard Hughes Medical Institute (HHMI) scientists have identified stem cells in the liver that give rise to ...

Hepatopulmonary syndrome (HPS) is an important cause of dyspnea and hypoxia in the setting of liver disease ... B receptors on pulmonary endothelial cells, leading to upregulation of endothelial ...

Our mission is to provide a state-of-the-art facility, expertise, and education in advanced quantitative light microscopy to support Drexel University’s research community The Cell Imaging Center (CIC ...

Discover how integrating advanced imaging, digital pathology, and molecular analysis, can refine fibrosis staging and ...