Table 1. Properties of loop diuretics. Diuretic Oral bioavailability Initial dose (mg) Maintenance dose (mg) Max dose (mg) iv. to p.o. conversion Elimination Duration of action (h) Torsemide: 80 ...

Loop diuretics are an essential component of therapy for patients with acute decompensated heart failure, ... Expand Table. Authors Info & Affiliations. More from Vol. 364 No. 9. Original Article ...

In CHF both the rate and absolute amount of loop diuretic absorbed can be reduced as a function of the HF state itself. In this setting, drug dissolution characteristics can assume added significance.

Furosemide is the most widely prescribed loop diuretic in the setting of systolic heart failure (HF), yet torsemide has been shown to have less inter- and intra-individual variation in bioavailability ...