Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National ...
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Chemists discover a key protein in how lysosomes workYamuna Krishnan at the University of Chicago have identified the protein responsible for a key role in how lysosomes work: how calcium ions get into lysosomes. Published in Science Advances ...
New research has made a breakthrough in understanding how our cells manage to stay healthy by recycling important fat ...
The hetero-octameric complex BORC recruits the small G protein ARL8 to mediate the transport and localization of lysosomes. BORC-ARL8 is an essential regulatory factor in the fusion of lysosomes ...
Dr. Lee will oversee the clinical development of Lycia’s lead programs, LCA-0061 for IgE-mediated diseases and LCA-0321 for ...
Breakthrough NUS discovery sheds light on cellular recycling mechanism and potential for treating rare diseases Singapore ...
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Alzheimer’s and Parkinson’s linked to aging brain’s failing waste disposalNew research uncovers how declining protein clearance mechanisms with age lead to Alzheimer’s, Parkinson’s, and other ...
A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, ...
These molecules, upregulated in cancer cells, are excreted through a surprising mechanism—lysosomal exocytosis. Researchers published their results in the Journal of Cell Biology on January 3 ...
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