The STING protein, known for helping cells fight viral infections by generating inflammation, also appears to function as a quality control sensor for organelles that serve as cellular waste disposal ...

Parkinson's disease is the second most common neurodegenerative disease in the world... | Genetics And Genomics ...

Tan used a lentivirus to express an enzyme called Turbo-ID in human cells, which sticks a biotin tag onto any protein within a ten-nanometer radius. Using a version of the enzyme which localizes to ...

This bubble then merges with the lysosome, where the contents are ... leading to the buildup of waste inside cells and human diseases. "We're excited about the potential of this research to ...

CRISPR technology uncovers new key genes and pathways linked to Parkinson’s disease, offering insights into risk and ...

Kanazawa University, report in Nature Communications how the targeted suppression of lysosome function may lead to brain ...

A longstanding mystery in Parkinson's disease research has been why some individuals carrying pathogenic variants that ...

On screening human cells to identify proteins that shuttled from the cytosol ... because their activation coincided with genes that increased lysosome production. TFEB is also an ancient regulator of ...

Damage to the mitochondria, the 'power plants' of the cells, contributes to many diseases. Researchers now describe how cells with defective mitochondria activate a special recycling system to ...