The activity of these "switches" is regulated by their methylation status, chemical marks that can be added to or removed ...

Van Andel Institute scientists have developed an improved technique to comprehensively profile DNA methylation in single ...

Prior to 1980, there were a number of clues that suggested that methylation might play a role in the regulation of gene expression.For example, J. D. McGhee and G. D. Ginder compared the ...

Researchers at the Hebrew University have developed an exceptionally accurate method for predicting chronological age from ...

Selecting the right DNA methylation sequencing assay is vital to generating robust and reproducible data on epigenetic modifications. ©iStock, undefined D NA methylation is a widely studied epigenetic ...

In addition, 77,789 MDSs (~41%) associated with 80,503 cis-acting sequence variants termed allele-specific methylation QTLs (ASM-QTLs). Taken together, the findings show that sequence variants ...

DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...

BUFFALO, NY — April 16, 2025 — A new research paper was published in Aging (Aging-US) Volume 17, Issue 3, on March 12, 2025, titled “DNA methylation entropy is a biomarker for aging.” ...

Abnormal methylation patterns are recognized as a hallmark of cancer. 4 Genes responsible for regulating cell cycle progression, DNA damage repair, and cell adhesion, for example, are frequently ...

DNA Methylation Influences Replication and Genome Organization. A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that ...

BACKGROUND: The association of overall cardiovascular health (CVH) with changes in DNA methylation (DNAm) has not been well characterized. METHODS: We calculated the American Heart Association’s ...