3e–f). It should be noted that uninfected macrophages, adjacent to infected macrophages, did not show vesicles containing GFP, ruling out endocytosis of Mtb-derived material (Supplementary Fig.

electron and nano-scale ion microscopy), allows researchers to visualise the distribution of TB drugs in Mtb-infected human macrophages at high resolution, for the first time. A test-case TB drug ...

they are engulfed by host lung macrophages and trapped inside intracellular vesicles called phagosomes. Mtb prevents the phagosome from merging with a lysosome, which otherwise would kill the ...