Here, the authors characterize the association of fucosylated Hp in sepsis progression and identify a macrophage population expressing a receptor for fucosylated Hp, highlighting its inflammation ...

catecholamines may also exert some proinflammatory effects through the 2 aderenoreceptor on macrophages. Wang et al. decreased mortality from sepsis in mice, using nicotine to activate the ...

Mitochondria, often seen as cellular powerhouses, play a surprising role in immune regulation. Researchers found that ...

"Therapies aimed at improving mitochondrial activity could benefit inflammatory diseases such as inflammatory bowel disease, sepsis ... ETC function also controls macrophages, or specialized ...

CD39 targeting therapies are emerging as a promising strategy for modulating immune responses in a range of diseases. CD39 serves as a vital ectonucleotidase that influences the purinergic signaling ...

Setting. The PICU at the Helen DeVos Children's Hospital (Grand Rapids, MI). Patients. The records of eight critically ill children presumed to have secondary hemophagocytic lymphohistiocytosis at ...