In 3D cell culture, rather than growing as a layer, cells are cultured in a three-dimensional shape in a gel matrix, or in the form of spheroids or organoids. 3D cultures can be used as model systems ...

Using donated lip tissue, they have created cell lines which can be grown indefinitely to make 3D models for advancing lip biology research and testing repairs for conditions like cleft lips ...

In this webinar, learn how scientists use advanced human brain models to uncover treatment strategies for complex ...

More information: Immortalization of patient-derived lip cells for establishing 3D lip models, Frontiers in Cell and Developmental Biology (2024). DOI: 10.3389/fcell.2024.1449224.

In fact, over 90 percent of drug candidates that show promise in preclinical studies ultimately fail in clinical trials, largely due to the limitations of traditional models. 3D cell culture provides ...

Researchers in the lab of April Kloxin, Thomas and Kipp Gutshall Development Professor, are engineering unique materials as well as 3D cell culture and disease models. Now, the group is using Inventia ...

Scripps researchers have developed the first 3D model of an entire cell in molecular detail, which has been described in a recent “Journal of Molecular Biology” article. One of the paper’s ...

In addition to readouts on cell viability, the Cell Painting assay was adapted for the 3D tumor model. These tumoroids were formed from primary cells isolated from a patient-derived tumor explant ...

Monocytes, B cells, and T cells readily squeezed through the microchannels. While T cells and monocytes infiltrated AD cultures more than they did control cultures, the opposite was true of B cells, ...

These 3D model brains with cells from several people are first of their kind. Chimeric brain ‘organoids’ promise to help reveal individual variation in brain development and in drug responses. ...

As researchers explore therapeutic strategies for more complex and heterogeneous diseases the need for more physiologically relevant models has never been greater. Researchers are increasingly looking ...