First, the recommended work-up for patients starting methotrexate therapy is superb and represents what is perhaps the single most pristine element of the 10 recommendations.

Methotrexate continuation significantly increases the risk for future fractures in patients with insufficiency fractures of ...

Daily oral treatment with T-614, a member of the methanesulfonanilide family of cyclo-oxygenase 2 inhibitors, might be an alternative to weekly methotrexate therapy for rheumatoid arthritis (RA).

The drug is called methotrexate. It’s not new—it’s been around since the 1980s and is commonly used to treat autoimmune ...

Pegloticase therapy for uncontrolled gout does not appear to significantly increase the risk for cardiovascular (CV) or thromboembolic (TE) events, despite the potential for increased gout flares ...

The findings highlight the potential benefits of newer biologics targeting IL-12, IL-23, and IL-17 while also raising ...

Considering taking supplements to treat methotrexate toxicity? Below is a list of common natural remedies used to treat or reduce the symptoms of methotrexate toxicity. Follow the links to read ...

IL-23, and IL-17 were associated with a lower rate of serious infections among older adults with psoriatic disease, a ...

Methotrexate is prescribed for psoriasis and certain cancers. It's a generic medication, available as the brand-name drugs Trexall, Xatmep, and more. It comes as an injectable IV solution, self ...

Filgotinib, a Janus Kinase 1 inhibitor, remains well-tolerated for up to 8 years with consistent efficacy in patients with rheumatoid arthritis, according to data published in RMD Open. The findings ...

Methotrexate sodium 2.5mg; scored tabs. Be fully familiar with this drug's toxicity before use. Obtain baseline and monitor CBCs for myelosuppression, and hepatic, renal and pulmonary function ...