Albers and colleagues are interested in whether olfactory dysfunction — the sometimes-subtle loss of sense of smell — can ...

Microglia, the brain's immune cells, usually serve as diligent guardians. They eliminate intruders such as microbes and clear ...

Common treatments may not be as effective for women as they are for men, mouse model reveals In a nutshell Research reveals ...

But new data from a recent clinical trial suggests that a previously discontinued experimental drug, called gantenerumab, ...

Notably, microglia spatially associated with amyloid plaques exhibited increased expression of TREM2 and ApoE compared to ...

Researchers found that accelerating the brain's waste removal system could have tremendous implications for our memory.

A comprehensive Thought Leaders Invited Review in Brain Medicine highlights the crucial role of CD2-associated protein (CD2AP ...

at immune cells known as microglia. Vital in both developing and mature brains, these cells help shape neurons, control how they communicate, keep an eye out for pathogenic intruders, and mediate ...

Lastly, certain genes, like TREM2 and APOE, are more active in microglia in response to treatment, helping these cells remove amyloid beta plaques, according to the findings. "A long-standing ...

Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...

"We found a way to exploit this flexibility by using forskolin to push these cells into a non-dividing, neuron-like or microglia-like state." Glioblastoma is notoriously difficult to treat ...