An innovative approach to modeling PD using PSC-derived midbrain-striatal assembloids and get to know their advantages compared to other disease models; How 3D light sheet microscopy works and how it ...

In a recent review published in the npj Parkinsons Disease, a group of authors explored the use of human midbrain organoids (mini 3D organ models) in Parkinson’s disease (PD) (movement disorder ...

This webinar will focus on generation of human midbrain organoids for the study of Parkinsons Disease. In order to simplify the workflow, an established method for 2-D differentiation of floor plate ...

Research on human brain development and neurological diseases is limited by the lack of advanced experimental in vitro models that truly recapitulate the complexity of the human brain. Here, we ...

Thus, for the first time, drug effects can be assessed on a single-cell level within a complex 3D cell environment in a fully automated high-throughput workflow. “The combination of production and ...

THIS book consists of a detailed account of a model of the medulla oblongata, pons Varolii and mesencephalon, which was made in the anatomical laboratory of the Johns Hopkins University by a ...

The midbrain in these fish, it turns out, may serve as a useful model for how mammals and other vertebrates, including humans control vocal expressions, according to Cornell behavioral research ...

The midbrain in these fish, it turns out, may serve as a useful model for how mammals and other vertebrates, including humans, control vocal expressions, according to Cornell University behavioral ...

Stimulant use disorders are associated with deficits in striatal dopamine receptor availability, abnormalities in mesocorticolimbic resting-state functional connectivity (RSFC) and impulsivity. In ...

In a recent review published in the npj Parkinsons Disease, a group of authors explored the use of human midbrain organoids (mini 3D organ models) in Parkinson’s disease (PD) (movement disorder ...