Oxidant accumulation also causes HDL to promote the formation of LDL-derived oxidized lipids and, hence, become proinflammatory Abbreviations: ABCA-1, ATP-binding cassette transporter A-1 ...

Although cholesterol and TG serve several important functions within the body, they are insoluble particles and must be packaged into lipoproteins in order to circulate in the plasma, from sites ...

Figure 1: Steady-state mRNA levels of genes that are regulated by Tcf1. Figure 4: Bile acid concentrations are increased in the serum, stool and urine of Tcf1 −/− mice. Figure 5: Tcf1 is a ...

Low levels of HDL and high levels of LDL cholesterol are both important predictors of cardiovascular disease. LDL cholesterol levels are effectively lowered by statin therapy, significantly ...