During development, neural crest cells, the precursors of neurons in ... Application of exogenous laminin-111 suppressed NCC migration in an organ culture model, whereas YIGSR, a laminin β1 ...

"Until this work, what was missing was whether these molecular pathways act within neural crest stem cells to promote migration," said Morrison. "Our finding that these pathways are all expressed ...

Neural crest is a unique cell population induced ... significantly inhibited proliferation and enhanced cell migration. The data implicate NCCs as a target cell population for retinoic acid ...

Science News sponsorship position. The two knew that other scientists had linked defects in neural crest cell migration to spotted coat colors, short jaws and small adrenal glands. Working with ...

The Wei lab is interested in the regulation of cell signaling and tissue homeostasis by metalloproteinases and other proteins in development and disease. Project 1. The mechanisms of neural crest ...

which requires a long-term cell culture and subsequent cell transplantation into host animals. We aim to establish an in vivo directed reprogramming technology with neural crest cells as a model.

Intro text here... Abnormal neural crest cell development is associated with numerous pathologies including craniofacial malformations such as cleft lip and cleft palate, rare syndromes, and ...

In contrast to neural crest-derived stem cells, which have a limited self-renewal capacity, pNSCs closely resemble brain-derived NSCs and show the ability to sustain neurogenesis over an extended ...