Homologous recombination is one mechanism for repairing double-stranded DNA breaks. It involves the exchange of nucleotide sequences to repair damaged bases on both strands of DNA through the ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

Impact of Homologous Recombination Deficiency on Outcomes in Patients With Triple ... HRD scores were calculated from genome-wide allele-specific copy number results and comprised telomeric allelic ...

Homologous recombination DNA repair deficiency (HRD) is a therapeutic biomarker for sensitivity to platinum and poly(ADP-ribose) polymerase inhibitor therapies in breast and ovarian cancers. Several ...

Frank Hartung, Stefanie Suer, Holger Puchta, Two Closely Related RecQ Helicases Have Antagonistic Roles in Homologous Recombination and DNA Repair in Arabidopsis Thaliana, Proceedings of the National ...