Throughout history, many viral diseases have proven difficult to treat. However, recent research into synthetic drugs has ...

In addition to their role in nucleic acids, purines are involved in various cellular metabolic ... and infectious diseases. Purine analogues, such as fludarabine and cladribine, are used in the ...

Kossel isolated cytosine from calf thymus tissues and found that it was a component of nucleic acids. This discovery ... primarily females. Cytosine Analogs in Chemotherapy and Antiviral Treatments ...

Among these are a chelatase (which catalyzes the insertion of copper ions into prophyrins-- this is the only major nucleic acid enzyme selected using a 'transition-state analogue' technology, such as ...

Target validation is the process by which the predicted molecular target – for example protein or nucleic acid – of a small ... activity-relationship of analogs of the small molecule ...

A nucleic acid is a long molecule made up of smaller molecules called nucleotides. Nucleic acids were discovered in 1868, when twenty-four-year-old Swiss physician Friedrich Miescher isolated a ...