In their study, the researchers discovered that there is a correlation between the rise in p16 during cellular aging and the increase in PD-L1 levels. They also worked out the molecular mechanism ...

Scientists call aging, inflammatory cells senescent cells ... one set highly expresses the gene p16 and the other highly expresses p21. Past experiments have shown that if you purge either ...

They focused on markers of biological aging, including cellular senescence ... radiation therapy more often had detectable levels of p16 INK4a — a biomarker of senescence — after treatment ...