Various members from each phosphatase group are enriched or exclusive to the nucleus and often have associated regulatory subunits that have a targeting role. In the DNA-damage response ...

"I think it's amazing that the crystal structure told us about this phosphatase activity," says Nemazee. "To discover new enzymatic activity is unheard of in structural biology. It's only because ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

Cellular and molecular biology, protein tyrosine phosphorylation ... MK-STYX is a novel protein included in the dual specificity mitogen-activated protein kinase phosphatase class that lacks the ...