Figure 1: PCP signalling is required for zebrafish neural tube formation ... Anterior membrane localization of Gfp-Pk as a marker of planar polarity. For transverse sections, embryos were fixed ...

PCP stands for 'planar cell polarity'. Two components are especially important to this pathway: the molecules Fzd7a and Vangl2. "When we deactivated the genes for these molecules in zebrafish ...

Researchers found that this process is largely regulated by the PCP (planar cell polarity) signaling pathway, particularly molecules Fzd7a and Vangl2. When these two molecules were genetically ...

Postdoctoral Scholar Yue Ban, Professor Yimin Zou, and their colleagues provide promising new evidence Oct. 6 in the journal Science Advances that the "planar cell polarity," or PCP, a powerful ...

This is called planar cell polarity (PCP). Tissues will not form correctly if cell polarity formation is impaired, and malformation can lead to the development of various diseases. Furthermore ...

"The planar cell polarity (PCP) pathway is known to control alignment of cells within the organism, and errors in PCP result in a variety of syndromes," said Michael L. Levin, Ph.D., senior author ...

PCP stands for 'planar cell polarity'. Two components are especially important to this pathway: the molecules Fzd7a and Vangl2. "When we deactivated the genes for these molecules in zebrafish ...