The nuclear pore is a protein-lined channel in the nuclear envelope that regulates the transportation of molecules between the nucleus and the cytoplasm. In eukaryotic cells, the nucleus is ...

Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its ...

A Vanderbilt-led research team has made a significant breakthrough in developing advanced dialysis membranes using atomically thin materials like graphene. These innovative membranes, called ...

Proteins can also refold on the trans side of the pore after passing through. In another study using this technology, we actually have to unfold a protein twice: once before it can go through the ...

The method cannot be used to decode protein sequences without a known reference for comparison, however. That’s because not only does the amino acid at the pore’s entrance affect the ion current, but ...

Nuclear pore complexes are the guardians of the human ... Those channels are filled with specialized proteins called FG-nucleoporins, which act as bouncers at the entrance door.

Members of the RTX family of protein toxins are functionally conserved among an assortment of bacterial pathogens. By disrupting host cell integrity through their pore-forming and cytolytic ...

Researchers develop graphene-based dialysis membranes that enhance filtration efficiency while reducing protein loss for improved treatment.