During a Case-Based Roundtable® event, Vamsidhar Velcheti, MD, discussed the TRIDENT-1 trial and practical considerations for ...

The PANAMutyper ROS1 diagnoses whether there is a ROS1 mutation based on polymerase chain reaction (PCR). Patients who test positive for the ROS1 gene are prescribed ROS1 inhibitors for treatment.

ROS1 is a rare mutation found in fewer than 2% of NSCLC cases. Currently there is a lack of treatments for ROS1-positive NSCLC, especially for people whose lung cancer has spread to the brain.

The patient's cancer originally had a ROS1 gene rearrangement ... using RNA next-generation sequencing (RNA NGS), an advanced test that can find mutations that standard genetic tests might ...