Some of the earliest, most complete descriptions of tumor cell chromosomes were provided by the great German cytologist Theodor Boveri, considered by many to be first cancer geneticist.

Bakhoum is a physician-scientist and cancer biologist at Memorial Sloan Kettering ... Learn about our Editorial Policies. Numerous errors in chromosome segregation during cell division can lead to the ...

When X-linked genes evade silencing on the “inactive” chromosome in XX cells, some protect women from diseases such as cancer, but others seem to promote conditions such as autoimmunity. Amber Dance ...

They exist as circular pieces of DNA in the nuclei of tumor cells ... chromosomes. Transcription of the amplified ecDNA genes can promote oncogenic processes, such as the increased expression of ...

The researchers have discovered a wealth of new interactions and have identified potential new targets for cancer therapy, as reported in the journal Nature. The researchers modified human cells ...

brings us closer to understanding the mechanisms behind aging and cancer. Before cells divide, they replicate the double-stranded DNA of each chromosome. The replication machinery does a good job ...