In 1991, Soriano et al. [16] published the first study on the use of norfloxacin to prevent an episode of SBP in patients with cirrhosis and low ascitic fluid total protein concentration (<1.5 g/dL).

2009;24(9):1494-1503. With the application of molecular approaches, efforts towards measuring the bacterial load using DNA in SBP patients have recently been made. Although not predictive of the ...