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GEN10mon
Modeling Clonal Evolution in Hematopoietic Malignancies
Characterizing clonal evolution in blood cancers like ... of cellular differentiation using flow cytometry and single cell RNA sequencing, recently integrating the ScaleBio Single Cell RNA Kit ...
Single-cell RNA sequencing of bone metastases from multiple cancer types reveals three distinct immune archetypes
Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not ...
The Scientist2y
Finally, Scientists Sequence Single Cells with Long-Read Technology
More recently, scientists have gained the ability to perform single-cell sequencing, which can reveal rare variations between cells and the evolution of cell lineages ... acquire mutations—known as ...
EurekAlert!2d
Childhood kidney cancer has millions of genetic changes, opening door to possible treatments
By harnessing the latest genomic sequencing technology, researchers reveal hidden mutations in childhood kidney cancer, Wilms ...
Science Daily2y
Novel, sensitive, and robust single-cell RNA sequencing technique outperforms competition
Single-cell RNA sequencing (scRNA-seq) is one of the most important methods to study biological function in cells, but it is limited by potential inaccuracies in the data it generates. Now ...
EurekAlert!1mon
Genome Research publishes a special issue on long-read DNA and RNA sequencing applications in biology and medicine
When applied to an ovarian cancer sample, LongSom detected clinically relevant somatic SNVs that could not be detected with short-read single-cell RNA-seq and ... 2025. Evolution of genome-wide ...
Phys.org1y
New approach to single-cell RNA structure sequencing unveils biomarkers for human development and disease
Named Sc-SPORT for Single Cell Structure Probing Of RNA Transcripts, this new approach is able to identify biomarkers crucial for human development and disease, based on shape rather than sequence ...
The Scientist2y
Single Cell Sequencing in a Nutshell
In contrast, single cell sequencing allows DNA or RNA from individual cells to be amplified and sequenced, capturing each cell’s uniqueness. 2 Scientists often use single cell sequencing to detect ...
Medical Xpress2y
Single-cell RNA sequencing maps immune cell heterogeneity in mice with allogeneic cardiac transplantation
More information: Zhonghua Tong et al, Single-Cell RNA Sequencing Maps Immune Cell Heterogeneity in Mice with Allogeneic Cardiac Transplantation, Cardiovascular Innovations and Applications (2023 ...
Nanowerk11mon
Single-Cell Sequencing Unveils Genetic Secrets of Individual Cells
What is Single-Cell Sequencing? Single-cell sequencing is a revolutionary technology that allows researchers to analyze the genetic material of individual cells, providing unprecedented insights into ...
C&EN8mon
Researchers can identify a person by sequencing RNA from individual cells
An individual’s genome is identifiable. But datasets of RNA sequences from single cells are like a blurry photocopy of the genome. The sequence numbers are small, the data are noisy, and the ...