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What role do single nucleotide polymorphisms play in this? In terms of this study, a low F ST value for a SNP can be interpreted to mean that individuals from the subpopulation tend to share ...
Such studies would employ a dense map of single-nucleotide polymorphisms (SNPs) to detect association between a marker and disease based on LD between the marker and a disease-risk gene variant.
Single nucleotide polymorphism microarrays have introduced the possibility of unbiased association screens, or GWAS, but can also be utilized for very-high-density linkage analysis. The first use ...