The ensemble of skeletal muscles can be considered the largest metabolic and endocrine organ of the human body. The more than ...

New mechanisms discovered that show how development-dependent disruptions in mitochondrial function lead to premature skeletal aging.

and that dGTP was by far the most abundant nucleotide in the mitochondria of most tissues. In heart muscle and skeletal muscle, for example, they found that dGTP represented 85% to 91% of the ...

Research has already established that pancreatic β-cells from diabetic patients exhibit abnormal mitochondria and reduced energy production. Skeletal muscle cells, visceral fat, and liver tissues ...

The team found that MCT1 regulates mitochondrial biogenesis of skeletal muscle and exercise activity, and the deletion of the ...

The pursuit for the elixir of eternal youth has fascinated scientists for centuries. Yet, natural ageing—marked by the ...

1 However, exercise causes mechanical stress in skeletal muscles; this ... to examine and compare the mitochondria from the two types of mice, since mitochondria power the muscles. They extracted ...

Nowadays, the prevalence of sedentary lifestyles and high-caloric diets leads to an imbalance between energy intake and ...

Semaglutide promising alternative treatment for chronic myopathy of hyperkalemic periodic paralysis suggests a case report ...

Widespread neuronal mitochondrial complex I (CI) deficiency was recently reported to be a characteristic in a subgroup of individuals with idiopathic Parkinson's disease (PD). Here, we sought to ...

Researchers have discovered that a development-dependent, premature impairment of mitochondrial respiration is responsible for speeding up the process of skeletal aging. The researchers undertook ...