Proteins that trigger cell senescence occupy much of the literature on aging, but a small RNA moves into the limelight. Kamal is a freelance science journalist based in the UK with a PhD in virology ...

Further analysis of the genes transcribed from the genomic island revealed that the 3'UTR of mRNA was processed to generate ManS, a novel small noncoding RNA of 80 nt in length. Importantly, ManS ...

See how small bits of non-coding RNA target mRNA for destruction and regulate gene expression. Evidence has also shown that siRNA is involved in antiviral defense in certain plant and animal species.

Researchers at Case Western Reserve University have discovered molecules that present the potential to drive the development ...

and their diversity of functions has led to the hypothesis that an "RNA world" may have preceded the evolution of DNA and proteins (Gilbert, 1986). Small interfering RNAs (siRNAs) are yet another ...

RNA interference (RNAi) is a cellular mechanism that uses small RNA molecules, such as small interfering RNAs (siRNAs) and miRNAs, to silence gene expression. These small RNAs can bind to ...

The fitRNA function appears similar to that of microRNAs, small segments of RNA (also once considered junk) that inhibit genes' protein-building functions—but there's a significant difference ...

WALTHAM, Mass.--(BUSINESS WIRE)--Arrakis Therapeutics, a biopharmaceutical company pioneering the discovery of a new class of small molecule medicines that directly target RNA, today announced ...

Given the growing antibiotic resistance crisis, novel ways to target bacterial infections are becoming increasingly important. One potential strategy is to manipulate bacterial genes at the ...

Researchers at Purdue University have developed NuFold, a machine learning tool that predicts 3D RNA structures from sequences. Dubbed the RNA equivalent of AlphaFold, NuFold bridges the gap in ...

The 3rd RNA- Targeted Drug Discovery Summit returns as the most comprehensive and definitive event for the RNA targeting small molecule community to not only address key challenges of the field ...

Arrakis’s DM1 drug program represents a rationally designed small molecule genetic medicine directed at a pathogenic RNA to achieve reversal of myotonia in an animal model of DM1. Utilizing the ...