One such medication is spironolactone, a water pill commonly prescribed to treat conditions like high blood pressure and heart failure that has a number of off-label uses. These include managing ...

Second, might spironolactone be equally effective, if given earlier than other medications, that is, as a third antihypertensive agent? One might anticipate that beyond meeting blood pressure ...

A mineralocorticoid receptor antagonist that blocks excess aldosterone and reduces fluid volumes, spironolactone is the ...

Amiloride, a potassium-sparing diuretic, was noninferior to spironolactone in reducing home-measured systolic blood pressure (BP ... but the efficacy of these drugs has not been directly compared ...

Retention of sodium and water increases blood pressure. Like all drugs, spironolactone does have side effects. We in medicine try to find a drug with minimal side effects to the patient that we ...

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