News

Structure of DNA repair complex reveals workings of powerful cell motor. ScienceDaily. Retrieved May 18, 2025 from www.sciencedaily.com / releases / 2011 / 03 / 110327191201.htm.
Without other factors usually found in meiotic cells, the BRCA2 in these MEILB2-positive cancers might not get to the DNA breakpoints. Having a structure of this complex in hand, researchers may ...
Researchers solve structure of BRCA2 protein complex important in DNA repair. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2021 / 08 / 210813120006.htm ...
A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and protects replicating DNA in dividing cells. This new structural and ...
image: Three-dimensional structure of the yeast Mec1-Ddc2 complex, a homolog of human ATR-ATRIP. The genomes of eukaryotic cells are under continuous assault by external and internal factors. All ...
Figure 1: The X-ray crystal structure of the Aptx–DNA–AMP–Zn 2+ quaternary complex. DNA-protein complementarity explains how Aptx conducts structure-specific DNA binding and deadenylation of ...
Figure 1: Generation of 8-oxoguanine (oxoG), its recognition by human 8-oxoguanine DNA glycosylase (hOGG1) and overview of the structure-based trapping strategy used here to obtain a complex of ...
The Ku heterodimer forms a cradle in which broken DNA strands rest whilst being repaired. Login. Subscribe. News; Magazines. An Interactive Experience. Current Issue. May 2025. View this Issue.
Though scientists have learned much about DNA damage and repair over the past 50 years, important outstanding questions remain. One particularly bedeviling puzzle is how a repair protein called the ...
A DNA repair complex known as CST, which suppresses homologous recombination, has been identified as a key factor in resistance to PARP inhibitors in BRCA1-deficient cancer cells.