THE ever-increasing number of case reports of renal complications in sulfonamide drug therapy indicates that neither the mechanism of their production nor the means of preventing them is yet ...
Sulfanilamide was administered in amounts ... Nature of renal tubular mechanism for acidifying urine. Am. J. Physiol. 144:239–254, 1945.
That all changed in 1938, after the deaths linked to Elixir Sulfanilamide had become a national scandal. Six years earlier, German pathologist and bacteriologist Gerhard Domagk discovered that a ...