Dr. Roddy O'Connor explores "hit & run" serial killing in CAR T cells, discussing how metabolic reprogramming influences ...

Between the axon of a transmitting neuron and the dendrite of a receiving neuron is a gap called the synapse—the site at which signals are passed between the brain cells. The nervous system ...

Furthermore, we currently have little understanding of the functional states of synapses on a cell-assembly basis. What is the overall signaling impact of synaptic inputs at physically non ...

In research published in Cell Reports, Harnett and his team show how individual neurons can contribute to both parts of this ...

Scientists have uncovered a crucial pathway that links brain cell activity to the activation of genes responsible for ...

Cell adhesion molecules (CAMs) play a crucial role in the development and maintenance of synapses, which are the connections between neurons that allow for communication in the brain. Recent ...

To understand how these brain cells exchange information through their synapses (junctions to exchange chemical 'messages'), the team of Prof. Joris de Wit (VIB-KU Leuven Center for Brain and ...

Led by first author Dr. Ahmed Gad, postdoctoral associate in Ahmed's lab, the research team examined molecular dynamics at the immune synapse. The team biopsied the CAR T cell immunological ...

The new research, published in the journal Cell, demonstrates how a specific configuration of electrical synapses enables animals to make context-appropriate choices, even when faced with similar ...

A recent study has uncovered key insights into the differing tumour rejection behaviours of chimeric antigen receptor T cells ...

Molecular dynamics at immune synapse lipid rafts influence the cytolytic behavior of CAR T cells. Science Advances , 2025; 11 (2) DOI: 10.1126/sciadv.adq8114 Cite This Page : ...