An efficient total-synthesis pathway with extraordinary flexibility ... against bacteria known to be resistant to tetracycline, penicillin, methicillin and/or vancomycin. These derivatives were ...

The last time a new class of antibiotics reached the market was nearly three decades ago—but that could soon change, thanks to a discovery by researchers at McMaster University.

Piperacillin, an antibiotic in the same class as penicillin, effectively cured mice of Lyme disease at 100-times less than the effective dose of doxycycline, the current gold standard treatment. At ...

Symptoms that persist long after Lyme disease is treated are not uncommon - a 2022 study found that 14% of patients who were diagnosed and treated early with antibiotic therapy would still develop ...

For the first time in three decades, researchers believe they have identified a new class of antibiotics. Teams at McMaster University in Ontario, Canada and the University of Illinois, Chicago ...