Although systematic reviews are ranked as havingthe highest level of evidence, the strength of the evidenceactually offered by a systematic review dependson how well the review is conducted.

The phenomenon of cancer overdiagnosis, the diagnosis of a malignant tumour that, without detection, would never lead to ...

Design Systematic review. Eligibility criteria Criteria for eligibility ... Descriptive synthesis was performed using the levels of evidence according to the Oxford Levels of Evidence. Results Five ...

The evidence on the use of puberty blockers ... or their impact on mental and physical health, find two systematic reviews of the available research, published in the Archives of Disease in ...

The US Food and Drug Administration recently announced a major initiative to strengthen oversight of food additives and other ...

Despite 22 systematic reviews including 142 unique randomised clinical trials, there is mainly low level of evidence for the effectiveness of ACL rehabilitation interventions to improve symptomatic ...

A new systematic review has found only very low-quality evidence that substances claiming to treat or prevent alcohol-induced hangover work. The researchers call for more rigorous scientific ...

The committee will carry out an assessment and prioritization process for reviewing the current literature to determine whether the quality and availability of peer-reviewed published evidence is ...

This rapid review examines recent evidence both about telehealth’s efficacy by clinical area and about telehealth’s impact on utilization. We searched for systematic reviews and meta-analyses ...

The committee also indicated a level of certainty for each of its findings ... the committee first determined whether there was sufficient evidence to support a systematic review for each health ...