Notably, IFT20 clusters with TCRs at the immune synapse and associates with the ζ- and ɛ-chains of CD3 in response to TCR engagement. TCR–CD3 complex assembly is initiated in the endoplasmic ...
(1) A chimeric antigen receptor (CAR) is a modular, synthetic receptor that endows T cells with different targeting abilities. Several emerging engineering approaches aim to improve the safety, ...
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Repertoire and Bristol Myers Squibb link on autoimmune disease vaccinesThe partnership will leverage Repertoire's DECODE platform to map the immune synapse and create targeted ... will utilise its DECODE T cell receptor (TCR)-epitope discovery platform and lipid ...
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