Notably, IFT20 clusters with TCRs at the immune synapse and associates with the ζ- and ɛ-chains of CD3 in response to TCR engagement. TCR–CD3 complex assembly is initiated in the endoplasmic ...
(1) A chimeric antigen receptor (CAR) is a modular, synthetic receptor that endows T cells with different targeting abilities. Several emerging engineering approaches aim to improve the safety, ...
The partnership will leverage Repertoire's DECODE platform to map the immune synapse and create targeted ... will utilise its DECODE T cell receptor (TCR)-epitope discovery platform and lipid ...