The Pre-Initiation Complex (PIC), which consists of Mediator, TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA polymerase II (pol II), governs the expression of all protein-coding and most non-coding ...
The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, Mediator, and RNA polymerase II (pol II). As a central integrator of both general and TF-specific regulatory signals, Mediator plays a ...