The team focused on T7 DNA polymerase’s thioredoxin binding domain (TBD), which has a structure similar to that of most thermostable polymerases, including Taq. Thioredoxin, which is ubiquitous in ...

Brock and Hudson Freeze in Yellowstone National Park in 1969. The bacterium is known for creating a protein called Taq polymerase—a heat-resistant enzyme that's active at unusually high ...

The technique, now a staple of every molecular biology lab, uses the thermostable Taq DNA polymerase to extend short single-stranded synthetic primers using the target DNA or cDNA as a template ...