All of these have been approved by the Food and Drug Administration to treat overactive bladder. The oldest are oxybutynin, available since 1976, and tolterodine (Detrol), first approved in 1998.

With the recent approval of tolterodine and oxybutynin XL ... Dosing ranges from 15 to 30 mg every 6 to 8 hours. The drug has strong anticholinergic side effects. Although it was available ...

Given these results of the OBJECT study, [12] a pharmacoeconomic model was developed comparing the two treatments, oxybutynin XL and tolterodine IR, using actual drug costs. Outcomes are estimated ...