Tramadol is available in immediate-release doses of 50 mg and 100 mg tablets and extended-release capsules of 100 mg and 150 ...

This study showed that a multiple-units SR formulation (capsule) produced smoother tramadol plasma concentration profiles than a single-unit SR formulation (tablet), whilst maintaining equivalent ...

Twenty-four healthy subjects (12 male and 12 female) were included in the trial. They were aged between 22 and 45 (mean 34.4) years, and had body mass indexes of 19.0-28.8 (mean 24.7) kg/m 2.