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Ubiquitin is a 76-amino-acid protein that is chemically unreactive ... molecular analysis using publicly available EST (expressed sequence tag) databases—gives the reader a real sense of ...
While its sequence made it part of a deubiquitinase ... They suggest that failing to remove ubiquitin from these proteins is linked to the disease. "Our findings not only add two additional ...
Our current efforts are directed toward understanding protein posttranslational modification (PTM) by ubiquitin (Ub) and ubiquitin-like proteins (ISG15 and SUMO) in cellular processes including ...
The researchers discovered that a protein called PARP10, which helps repair DNA, can be tagged with both ADP-ribose and ubiquitin. This dual modification is important when the immune system ...
A new strategy for delivering bulky PROTACs to cancerous cells successfully utilizes the CD36 protein pathway on cells’ surfaces.
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