Ubiquitination, a fundamental post-translational modification, plays a pivotal role in protein stability, cellular signaling, and gene expression, particularly in the context of CSCs.

Ovarian cancer, a leading cause of death among gynecological malignancies, has a poor prognosis and low 5-year survival rate, ...

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor ...

By unveiling the complex interactions between ubiquitination, cell death pathways, and cancer biology, this review lays the foundation for novel therapeutic strategies.