Ubiquitin marks proteins for degradation, whereby ubiquitin molecules can be combined in different types and numbers forming ...

Researchers have revealed for the first time how a key protein linked to Parkinson's mutates, leads to cell death in the ...

This new cryo-EM structure represents a remarkable advance in our understanding of how human PINK1 is stabilized” said ...

Ubiquitin-specific proteases play a critical role in regulating cell death pathways in breast cancer, affecting tumor ...

A new study has uncovered a molecular mechanism by which rice cells perceive viral infections and initiate antiviral response ...

Parkinson's Disease has an early onset form, which affects patients before they reach age 50, and is due to genetic mutations ...

The researchers have established that specific intracellular types of living bacteria possess special enzymes which allow them to permanently remove what is referred to as ubiquitin marking.

The precise regulation of the RIG-I-like receptors (RLRs)-mediated type I interferon (IFN-I) activation is crucial in antiviral immunity and maintaining host immune homeostasis in the meantime. Here, ...

Researchers have discovered more about PINK1, a protein that’s directly tied to Parkinson’s disease. A team from Walter and Eliza Hall Institute in Australia has shown how the protein attaches to cell ...

Researchers at the Max Planck Institute of Biochemistry (MPIB) have developed the new UbiREAD technology to decode the various combinations of ubiquitin molecules – the ubiquitin code – which ...