Researchers have found that no adjustment method fully resolves confounding by indication in observational studies, meaning when the validity of a study is threatened by unmeasured confounding, it ...

In the section Intractable unmeasured confounding in subgroups, we noted that possible examples of such subgroups include subjects with a diagnosed chronic disease, an age of greater than 70 years ...

Data analyses usually make assumptions (which may be explicit or, more commonly, implicit): for example, “no unmeasured confounding”. When assumptions are untestable their potential importance can ...

Propensity scores are useful in controlling for measured confounding in observational studies of medical treatments or risk factors, but neither propensity score methods nor multivariable ...

For this study, Fu and colleagues extracted data from 12 studies performed in Europe, Asia, North America and Australia, conducting a bias analysis for unmeasured confounding (the studies assessed ...

Here are some clues to the unmeasured confounding issues in CVD-REAL: The SGLT2 inhibitor cohort in both studies received more cardioprotective medications (statins, angiotensin-converting enzyme ...

(PhysOrg.com) -- Researchers at Boston University School of Medicine (BUSM) and Boston University School of Public Health have found that no adjustment method fully resolves confounding by ...

Although these studies have controlled for a number of potential confounders, the possibility of confounding by unmeasured factors remains. If maternal use of paracetamol was simply a marker of ...

Key Takeaways. Women with psoriasis show shorter drug survival for biologics, including IL-17/23 inhibitors, due to lower satisfaction and more frequent adverse events.