Purpose: The mechanism of action and pharmacokinetics of sirolimus when used as part of a drug-eluting stent (DES) and the efficacy and cost of using DESs versus bare-metal stents are discussed.

when compared with bare-metal stents (BMSs), in patients undergoing percutaneous coronary intervention. Use of these stents rapidly became widespread in clinical practice. However, reports of ...

Interv Cardiol. 2012;4(1):1557-1564. Although drug-eluting stents (DES) are more effective than bare-metal stent (BMS) in reducing restenosis rate, there is the need for a prolonged dual ...