T-cell activation involves two phases, enabling a more precise immune response. This insight may boost cancer immunotherapy effectiveness. A research team led by Wolfgang Kastenmüller and Georg ...

A team has identified a previously unknown phase of the immune response. The results challenge long-standing assumptions about the process called 'T-cell priming'. These new insights have significant ...

A team from the Max Planck Research Group for Systems Immunology at the University of Würzburg has identified a previously ...

The research groups led by Wolfgang Kastenmüller and Georg Gasteiger employed innovative microscopy techniques to observe how specific immune cells ...

The research groups led by Wolfgang Kastenmüller and Georg Gasteiger employed innovative microscopy techniques to observe how ...

This important work presents a stochastic branching process model of tumour-immune coevolution, incorporating stochastic antigenic mutation accumulation and escape within the cancer cell population.

Currently, there are six CAR T-cell therapy products approved by the US Food and Drug Administration (FDA), and more are expected to be approved in the next few years. Immune effector cells such as ...

A new study has revealed that a special group of cells in the intestines tamp down the immune responses caused by exposure to food proteins. Called 'tolerogenic dendritic cells,' these cells enable ...

Our immune systems develop to recognize what is foreign within our bodies. As immune cells are generated in the bone marrow and mature in other locations, they undergo processes that instruct which ...

Loss of immune function – that is ... T & B cells in aging The pool of naive cells is reduced, while effector memory and potentially dysfunctional late-differentiated cell numbers are increased.